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Honors Theses

• Cedarville University students Nick Camillone and David Mortenson competed at the Mason Cubing Challenge in Mason, Ohio, on Sept. Camillone’s highest placing was fourth in the blindfolded challenge while Mortenson’s highest placing was 14th in the 5x5 cube challenge.
• Skilled in Mac OS X Server, Microsoft Word, Performing Arts, Adobe Photoshop, and social media. Strong community and social services professional with a Bachelor's degree focused in Marketing.

Three Cups of Tea, Greg Mortenson, 2009, Juvenile Nonfiction, 32 pages. Tells the true story of a man who became lost and delirious after an unsuccessful trek to the top of K2, was saved by the locals of a remote Himalayan village, and kept his vow Teaching the Writing Process in High School, Jan 1, 1995, English language, 142 pages.

Date of Award

2015

Document Type

Thesis

Department

Biology

First Reader

Dr. Lori Hensley

Second Reader

Dr. Barbara Pemberton

Third Reader

Dr. Chris Mortenson

Abstract

Shooter Mortenson Mac Os Catalina

Triple Negative Breast Cancer (TNBC) is a difficult type of cancer to treat because it is negative for progesterone, estrogen, and HER-2 receptors. Because TNBC is negative for these three receptors, it does not respond to normal hormonal therapies. The purpose of my experiment is to see if different cannabinoids, compounds from the cannabis plants, could be used as alternative treatment options. These experiments employed three different cannabinoids: ajulemic acid, cannabidiol, and hemp oil. Cell viability was measured after 72 hours of treatment using a MTT assay. The results showed that the three cannabinoids could be used to effectively destroy the TNBC cells. We used this data to calculate the median lethal dose (LD-50), the concentration of the cannabinoid that can be given to destroy half of the cells. Our data suggest, cannabinoids could potentially be used as an alternative treatment for TNBC. However, much more testing would need to be done before it could be confirmed as a viable treatment option.

Recommended Citation

Dahl, Haley, 'The Effect of Cannabinoids on Triple Negative Breast Cancer Cells' (2015). Honors Theses. 183.
https://scholarlycommons.obu.edu/honors_theses/183

Shooter Mortenson Mac Os X

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